Category Archives: Vaccine

ShigETEC vaccine candidate has the potential to have a major impact on diarrheal diseases

VIENNA, 24-Sep-2020 — /EPR HEALTHCARE NEWS/ — Eveliqure Biotechnologies GmbH, an Austrian biotechnology company, today announces the initiation of clinical testing for its ShigETEC vaccine candidate, with the dosing of the first subject in a Phase 1 safety and immunogenicity study in Europe. ShigETEC is an orally administered vaccine candidate targeting Shigella and Enterotoxigenic E. coli (ETEC), two of the major pathogens responsible for diarrhoeal diseases in travelers to endemic countries, as well as a major threat to children living in low- and middle- income countries.

Currently no effective vaccines against these two pathogens exist and previous attempts to develop vaccines against Shigella and ETEC have failed. Eveliqure has employed a radically innovative approach based on a live attenuated Shigella vaccine strain rationally designed to provide broad, serotype independent protection against both Shigella and ETEC, and is developing the vaccine for both travelers to endemic countries and for children living in resource-poor countries. Following this initial Phase 1 study run in Hungary, further clinical development of ShigETEC will include Phase 1 testing in non-endemic adults, immune characterization of vaccine responses, vaccine formulation studies and clinical testing of ShigETEC in the pediatric population in resource poor-countries. These activities are supported by the EU-funded SHIGETECVAX international consortium of world-leading vaccine organizations – the European Vaccine Initiative, Eveliqure Biotechnologies, University of Gothenburg, icddr,b and PATH.

“Entering clinical development with ShigETEC marks a major milestone for Eveliqure, culminating from our extensive preclinical work performed over the past five years” – commented Gábor Somogyi, MD, MBA, Chief Executive Officer of Eveliqure. “We believe that ShigETEC has the potential to reduce the burden of diarrhoeal diseases for travellers, while also saving hundreds of thousands of children in endemic areas of the world”.

“Initiating the Phase 1 study for ShigETEC in adult volunteers is a crucial step towards establishing safety and immunogenicity of our vaccine candidate, and will help us define a well-tolerated, and effective schedule of dosing for our planned Phase 2 human challenge studies”. – commented Frank Malinoski MD, PhD, Chief Medical Officer of Eveliqure.

Compared to single pathogen approaches, ShigETEC has the potential to have a major impact on diarrheal diseases, protecting both travelers to the developing world and children in endemic populations.

SOURCE: EuropaWire

Blue Water Spa, a Raleigh NC Spa and Laser Hair Removal Center Donates $107,000.00 to Boys and Girls Clubs of Wake County

Blue Water Spa, a Raleigh laser hair removal center, donates $108,000 to the Boys and Girls Clubs of Wake County. Kile Law, president and founder of Blue Water Spa in Raleigh, NC attributes the donations to the loyalty and generosity of the clients and staff at Blue Water Spa.

“The Boys and Girls Clubs is an amazing organization. They need support of the community to continue their wonderful work,” says Kile Law. “We are a small business, but I know when we work together Blue Water Spa clients can do great things. The average donation was $37.11, but we all gave together to reach $100,000.00.” Blue Water Spa raised money by offering spa and laser hair removal in Raleigh at a redued price for people who donate to charity.

Blue Water Spa has been voted best medical spa in America for three consecutive years by American Spa Magazine. Raleigh Spa Specials at Blue Water Spa provide an opportunity for people who serve the community and/or donate time or funds to charity to receive luxury spa treatments at reduced prices. Blue Water Spa is the top provider of Botox and Juvederm in the Raleigh area and was recently designated an Allergan Black Diamond Provider. In 2011 Blue Water Spa supported over 120 local charities and non-profits. Blue Water Spa has donated more than 150,000 pounds of food to the Interfaith Food Shuttle of NC.

The North Raleigh spa provides luxury spa services in a beautiful lush atmosphere. Blue Water Spa laser center provides laser hair removal, laser skin tightening and laser vein therapy.

Kile Law is president and founder of Blue Water Spa, Kile has been recognized as Humanitarian of the Year in the Aesthetics industry by Aesthetics International. Under Kile Law’s leadership, Blue Water Spa has been voted best place to work in the Triangle by the Triangle Business Journal. Kile Law leads the spa’s philanthropic endeavors. In 2010 she was recognized by the Interfaith Food Shuttle of NC for a gift of 100,000 pounds of food to the Interfaith Food Shuttle.

Via EPR Network
More Healthcare press releases

Boots Is Joining The Pampers And UNICEF Tetanus Vaccine Initiative For One Month During The Forthcoming Campaign

Boots has announced that it is joining the Pampers and UNICEF tetanus vaccine initiative for one month during the forthcoming campaign.

Each year maternal and newborn tetanus kills approximately 30,000 mothers and 140,000 babies around the world. This is equivalent to one baby dying from tetanus every three minutes. In 2007 Pampers created a campaign to support UNICEF by supplying funding for tetanus vaccines in developing countries through the sale of its nappies.

Boots has pledged to join this year’s campaign for 4 weeks of the three month campaign. During this time Boots will match the donation made by Pampers on the sale of Pampers nappies sold through Boots stores. This means that for every specially marked Pampers pack sold in Boots stores, the funding for two vaccines will be donated to UNICEF, rather than one.

Caroline Gardner, Boots Buyer for Baby said; “Maternal and newborn tetanus was eliminated in the developed world almost 50 years ago and it is shocking that this disease can turn the joy of having a baby into tragedy in more than 40 countries still today. The Pampers project with UNICEF can transform lives and Boots is delighted to be joining this initiative and hopefully help to make a real difference to families’ lives.”

Last year Pampers provided UNICEF with the funding for over 15 million tetanus vaccines. This year, with support from companies such as Boots, Pampers is hoping to provide the funding for 32 million vaccines to help UNICEF support countries in eliminating maternal and newborn tetanus by 2012*.

The Pampers and UNICEF campaign runs from October to December 2008 and Boots joins the campaign for four weeks from late October **.

Pampers Brand Manager, Usama AlQassab, commented, “The Pampers-UNICEF campaign is now in its third year in the UK, and year-on-year we have increased the target of the number of vaccines we want to raise. Matched contributions, such as the campaign Boots are committing to, are a critical factor for us to reach this year’s target of 32 million vaccines”.

UNICEF UK spokesperson Mayaz Rahman said: “It is unacceptable that maternal and newborn tetanus still claim approximately 170,000 lives every year, even though they are easily preventable diseases. Our partnership with Pampers is invaluable in helping us to support countries in eliminating maternal and newborn tetanus by 2012, and we are delighted that Boots will be adding its support to the initiative for four weeks.”

UNICEF UK – registered charity number 1072612 – is on the ground in over 150 countries and territories to help children survive and thrive, from early childhood through adolescence. The world’s largest provider of vaccines for developing countries, UNICEF supports child health and nutrition, good water and sanitation, quality basic education for all boys and girls, and the protection of children from violence, exploitation, and AIDS. UNICEF is funded entirely by the voluntary contributions of individuals, businesses, foundations and governments.

About Boots
Boots is the UK’s leading retailer of beauty and health products, including baby products, with thousands of products from prestigious brands.

Boots Pharmacy Superintendent is responsible for healthcare advice provided within the Boots Pharmacy pages of is the trading name of Boots UK Limited (reg. 928555) an Alliance Boots company. All other information and advice on is the responsibility of Boots UK Limited.

Via EPR Network
More Healthcare press releases