Tag Archives: antibiotics

Palette Life Sciences unveils an online resource aimed at paediatric urologists, parents and caregivers in the UK dealing with vesicoureteral reflux (VUR)

SANTA BARBARA, CALIF., U.S.A. / STOCKHOLM SWEDEN, 4-Aug-2020 — /EPR HEALTHCARE NEWS/ — Palette Life Sciences, a fully integrated global life sciences company dedicated to improving patient outcomes, today announced the launch of Deflux.com/UK as part of its global expansion. Deflux.com/UK is a best-in-class online resource developed specifically for healthcare practitioners in the United Kingdom, as well as parents and caregivers managing children with vesicoureteral reflux (VUR). VUR, sometimes referred to as urinary or bladder reflux, is a serious paediatric urinary condition in which urine flows from the bladder through one or both ureters toward the kidneys.

Deflux.com/UK features important information about VUR, including symptoms, causes, risk factors and treatment options, such as Deflux®. Comprised of hyaluronic acid (HA) and dextranomer polysaccharides to form a gel, Deflux is a minimally invasive biocomopatible treatment for VUR. Endoscopic treatment with Deflux takes about 15 minutes in a day procedure setting, and generally allows the child to go back to normal activities the next day.

Deflux.com/UK also provides physicians with access to the Deflux Learning Center, a leading global education platform that features information and training for paediatric urologists and their peers who treat VUR as well as other paediatric urology conditions. The Deflux Learning Center includes clinical articles, educational videos and webinars, brochures, downloadable tools and The PedSpace podcast series, created for and presented by paediatric urology healthcare professionals.

“Deflux is an effective, minimally-invasive treatment option that many caregivers simply aren’t aware of,” said Dr. Marie-Klaire Farrugia, Consultant Paediatric Urologist and Clinical Director for Paediatric Surgery at Chelsea and Westminster Hospital. “My personal long-term experience with Deflux has proven its effectiveness and safety in reducing VUR and preventing UTI recurrence, thus avoiding use of long-term antibiotics. It is my hope that the new website initiative, which includes helpful resources for both physicians and caregivers, will help raise awareness and utilisation of this treatment option.”

“The entire Palette commercial team is excited to launch Deflux.com/UK, which we believe will help elevate the standard of care for VUR patients in the UK,” said Rich Low, Head of Marketing, Palette Life Sciences. “Deflux.com/UK will serve as a truly valuable resource for caregivers, providing critical information to paediatric urology healthcare professionals through the Deflux Learning Center, and to caregivers, connecting them to highly-trained specialists who provide high quality care.”

SOURCE: EuropaWire

NAICONS and NexThera Transfer Rights Of NAI-107, A New Anti-MRSA Antibiotic, To Sentinella Pharmaceuticals

NAICONS (New Anti-Infectives CONSortium) and NexThera Biosciences, Italian companies focusing on the discovery and development of novel anti-infective drugs, today announced that they have entered into an agreement with Sentinella Pharmaceuticals, Inc., a US-based pharmaceutical company established by Care Capital LLC, a leading life sciences venture capital firm. Under the terms of the agreement, Sentinella has acquired all rights to NAICONS’ proprietary lantibiotic technology, including its lead product candidate NAI-107, in exchange for an upfront cash payment, future development and commercialization milestones, royalties on future product sales and an equity stake in Sentinella. Lantibiotics represent a new class of natural products with potent bactericidal activity against gram positive bacteria including the multi-drug resistant pathogens MRSA and VRE.

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“This agreement represents an important recognition of NAICONS’s ability to discover and characterize innovative antibiotics with a novel mechanism of action”, stated Stefano Donadio, NAICONS’ Chief Scientific Officer. “Our technology is based on fermentation products and includes strong expertise in manipulating antibiotic-producing bacterial strains. This agreement further supports NAICONS’ mission of rebuilding the strong and successful Italian tradition in the antibiotic field.”

“Our partnership with a US-based pharmaceutical company represents the best opportunity to rapidly and successfully advance a potential life-saving drug into clinical development in its largest market. It also gives NexThera international visibility for developing additional anti-infective compounds”, said Daniela Jabes, NexThera’s Chief Executive Officer. “This agreement represents the first tangible result of the synergy between NAICONS’s discovery engine and NexThera’s development focus.”

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“We are delighted to be entering into this transaction with NAICONS and NexThera,” said David Ramsay, a Director of Sentinella. “The principals behind NAICONS and NexThera have a successful track record in the discovery and development of anti-infective products, including rifamycins, penems, dalbavancin and ramoplanin , and we hope to build on that success to develop and commercialize an important novel class of antibiotics for the treatment of multi-drug resistant nosocomial infections.”

Every year several million people worldwide acquire infections while in hospitals, with significant mortality rates. Continuing a trend that began several years ago, it is estimated that approximately seventy percent of hospital infections are currently caused by pathogens resistant to at least one class of existing antibiotics. Methicillin Resistant Staphylococcus aureus (MRSA) and Vancomycin Resistant Enterococci (VRE) are among the most dangerous nosocomial pathogens.

According to the Infectious Diseases Society of America, drug resistant bacteria represent a significant economic burden because of the need for costly drugs, extended hospital stays and lost working days. The annual cost of infections by drug-resistant pathogens has been estimated as nearly $5 billion in the U.S. alone.

Via EPR Network
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